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100 Articles About top-line

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BRIEF-Lilly's Cyramza meets Primary Endpoint in gastric cancer study

* LILLY REPORTS TOP-LINE RESULTS FROM CYRAMZA® (RAMUCIRUMAB) PHASE 3 STUDY IN FIRST-LINE ADVANCED GASTRIC CANCER

companyNews reuters.com

BRIEF-Medicinova Announces Positive Top-Line Results From Clinical Trial Of MN-166 (ibudilast) In ALS

* MEDICINOVA ANNOUNCES POSITIVE TOP-LINE RESULTS FROM THE CLINICAL TRIAL OF MN-166 (IBUDILAST) IN ALS

companyNews reuters.com

BRIEF-Auris Medical Reports Top-Line Results from Phase 3 Trial of AM-111 in Sudden Deafness

* AURIS MEDICAL HOLDING AG SAYS ANNOUNCED TOP-LINE RESULTS FROM THE HEALOS PHASE 3 CLINICAL TRIAL OF AM-111 IN SEVERE TO PROFOUND SUDDEN DEAFNESS

companyNews reuters.com

BRIEF-Spring Bank Pharmaceuticals announces positive top-line results from the second cohort of part A of the phase 2 achieve trial

* Spring Bank Pharmaceuticals announces positive top-line results from the second cohort of part A of the phase 2 achieve trial

companyNews reuters.com

BRIEF-Reata Pharmaceuticals says top-line data to be available in 2019 for omaveloxolone​

* Reata Pharmaceuticals Inc - ‍announces first patient enrolled in Part 2 of Moxie study of omaveloxolone for treatment of Friedreich's Ataxia​

companyNews reuters.com

BRIEF-Durect announces top-line results from the persist phase 3 trial of Posimir® did not meet primary efficacy endpoint

* Durect announces top-line results from the persist phase 3 trial of Posimir® (saber®-bupivacaine) did not meet primary efficacy endpoint

companyNews reuters.com

BRIEF-Myovant Sciences announces positive top-line results from Takeda's phase 3 study

* Myovant sciences announces positive top-line results from Takeda's phase 3 study evaluating efficacy and safety of Relugolix compared with Leuprorelin for treatment of uterine fibroids

companyNews reuters.com

BRIEF-Esperion Therapeutics - Phase 3 results for bempedoic acid expected in Q2, Q3 2018

* Esperion Therapeutics- bempedoic acid top-line results from studies 1, 3 and 4 are expected in Q2 2018, results from study 2 expected in Q3 2018

companyNews reuters.com

BRIEF-Zogenix announces positive phase 3 clinical trial of ZX008 in Dravet syndrome

* Zogenix announces positive top-line results from pivotal phase 3 clinical trial of ZX008 in Dravet syndrome

companyNews reuters.com

BRIEF-Astellas Pharma and Pfizer say positive top-line results from phase 3 prosper trial of XTANDI (enzalutamide)

* Co and Pfizer Inc announced that the Phase 3 PROSPER trial evaluating XTANDI®(enzalutamide) plus androgen deprivation therapy (ADT) versus ADT alone in patients with non-metastatic (M0) CastrationResistant Prostate Cancer (CRPC) met its primary endpoint of improved metastasis-free survival (MFS)

companyNews reuters.com

BRIEF-Amicus announces top-line phase 3 results for SD-101 in Epidermolysis Bullosa

* Amicus Therapeutics announces top-line phase 3 results for SD-101 in Epidermolysis Bullosa

companyNews reuters.com

BRIEF-Gemphire announces top-line data from royal-1 phase 2b clinical trial in hypercholesterolemic patients

* Gemphire announces top-line data from royal-1 phase 2b clinical trial in hypercholesterolemic patients

companyNews reuters.com

BRIEF-Pfizer announces positive top-line results

* Pfizer announces positive top-line results from the comparative reflections B7391003 study for PF-06439535, a potential biosimilar to avastin®1 (bevacizumab)

companyNews reuters.com

BRIEF-Neothetics says ‍LIPO-202 did not demonstrate improvement on any efficacy measurements

* Neothetics announces top-line results for phase 2 proof-of-concept study of LIPO-202 for the reduction of submental subcutaneous fat

companyNews reuters.com

BRIEF-Lexicon Pharmac reports positive late-stage data on diabetes drug

* Lexicon Pharmaceuticals reports positive top-line results in phase 3 intandem3 study for sotagliflozin in patients with type 1 diabetes

companyNews reuters.com

BRIEF-Amicus Therapeutics says co on track to report top-line data from essence study during Q3

* Says Amicus is on track to report top-line data from essence study during Q3 of 2017

companyNews reuters.com

BRIEF-Paratek announces completion of enrollment for oral-only omadacycline phase 3 skin study

* Paratek announces completion of enrollment for oral-only omadacycline phase 3 skin study, top-line data expected in mid-july Source text for Eikon: Further company coverage:

companyNews reuters.com

BRIEF-Alder Biopharmaceuticals top-line results from promise 1 expected later this quarter

* Alder Biopharmaceuticals Inc - top-line results from promise 1 expected later this quarter Source text for Eikon: Further company coverage:

companyNews reuters.com

BRIEF-Cara Therapeutics announces positive top-line data from Part A of Phase 2/3 Trial of I.V. CR845 in chronic kidney disease-associated pruritus

* Cara Therapeutics announces positive top-line data from part A of phase 2/3 trial of I.V. CR845 in chronic kidney disease-associated pruritus

companyNews reuters.com

BRIEF-Tigenix NV announces top-line one-year results from Caremi clinical trial

* Tigenix NV - announced top-line one-year results from Caremi clinical trial, an exploratory phase I/II study of Allocscs in acute myocardial infarction

rbssHealthcareNews reuters.com

BRIEF-Aviragen Therapeutics announces results from phase 2 study

* Aviragen Therapeutics announces top-line results from phase 2A RSV challenge study of bta585

governmentFilingsNews reuters.com

BRIEF-Tenax Therapeutics announces top-line results from phase 3 LEVO-CTS trial in cardiac surgery

* Tenax Therapeutics announces top-line results from phase 3 levo-cts trial in cardiac surgery

rbssHealthcareNews reuters.com

BRIEF-Aeterna Zentaris completes Zoptrex(tm) pivotal Phase 3 clinical trial in advanced endometrial cancer

* Aeterna Zentaris announces completion of Zoptrex(TM) pivotal Phase 3 clinical trial in advanced endometrial cancer; expects to report top-line results in April 2017

rbssHealthcareNews reuters.com

BRIEF-Eyegate Pharma announces positive top-line data from first-in-human pilot trial of ocular bandage gel

* Eyegate Pharma announces positive top-line data from first-in-human pilot trial of ocular bandage gel in corneal epithelial defects

rbssHealthcareNews reuters.com

BRIEF-Ocera announces top-line results for phase 2b study in hepatic encephalopathy

* Ocera announces top-line results for phase 2b study in hepatic encephalopathy

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BRIEF-Astellas and Ironwood report positive top-line results from phase III Linaclotide trial in Japan

* Astellas and Ironwood report positive top-line results from phase III Linaclotide trial for patients with chronic constipation conducted in Japan

companyNews reuters.com

BRIEF-Stallergenes Greer announces positive results of phase 3 study for allergic rhinitis

* Stallergenes Greer announces positive top-line results of phase 3 study for pediatric house dust mite-induced allergic rhinitis

rbssHealthcareNews reuters.com

BRIEF-Pfizer reports positive top-line results from phase 2 study of investigational clostridium difficile vaccine

* Pfizer announces positive top-line results from phase 2 study of investigational clostridium difficile vaccine for the prevention of c. Difficile infection

rbssHealthcareNews reuters.com

BRIEF-Otonomy announces positive top-line results from Phase 3 clinical trial

* Otonomy announces positive top-line results from phase 3 clinical trial of otiprio in patients with acute otitis externa Source text for Eikon: Further company coverage:

marketsNews reuters.com

BRIEF-Aeterna Zentaris announces top-line results of confirmatory Phase 3 trial of Macrilen

* Aeterna Zentaris announces top-line results of confirmatory Phase 3 trial of Macrilen

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BRIEF-Aevi Genomic Medicine top-line results for Phase 2/3 SAGA clinical trial expected in Q1 2017

* Aevi Genomic Medicine announces completion of enrollment for Phase 2/3 SAGA clinical trial of AEVI-001 (NFC-1) in MGLUR+ ADHD adolescents

governmentFilingsNews reuters.com

BRIEF-Agile Therapeutics announces positive top-line phase 3 results

* Agile Therapeutics announces positive top-line phase 3 results

governmentFilingsNews reuters.com

BRIEF-Inotek announces top-line results for MATRX-1

* Inotek announces top-line results for matrx-1, first phase 3 trial of trabodenoson for glaucoma

companyNews reuters.com

BRIEF-Neothetics initiates phase 2 proof of concept trial for lipo-202

* Expects to report top-line data from this trial in late Q2 2017

governmentFilingsNews reuters.com

BRIEF-Protalix Biotherapeutics says last patient enrolled in mid-stage trial

* Protalix Biotherapeutics - expects to report interim top-line results from study during first week of Jan 2017, and full results before end of Q1 of 2017

rbssHealthcareNews reuters.com

BRIEF-Lexicon reports positive top-line results in phase 3 study for sotagliflozin in patients with Type 1 diabetes

* Lexicon reports positive top-line results in second pivotal phase 3 study for sotagliflozin in patients with type 1 diabetes

governmentFilingsNews reuters.com

BRIEF-Diamedica announces positive top-line results from DM199 bridging clinical trial

* Diamedica announces positive top-line results from DM199 bridging clinical trial

marketsNews reuters.com

BRIEF-Acadia Pharmaceuticals announces positive top-line results from phase ii study of pimavanserin for alzheimer's disease psychosis

* Acadia Pharmaceuticals announces positive top-line results from phase ii study of pimavanserin for alzheimer's disease psychosis

rbssHealthcareNews reuters.com

BRIEF-Egalet announces results from intranasal human abuse potential study of Egalet-002

* Egalet announces positive top-line results from an intranasal human abuse potential study of Egalet-002

marketsNews reuters.com

BRIEF-Amgen receives positive response from EMA for its single-dose delivery injection Repatha

* Top-line results from approximately 27,500-patient event-driven fourier study are anticipated in q1 of 2017

rbssHealthcareNews reuters.com

BRIEF-Concert Pharmaceuticals announces CTP-543 positive top-line phase 1 results

* Concert pharmaceuticals - phase 2A trial expected to commence in Q1 next year and topline primary outcome data expected by end of 2017

governmentFilingsNews reuters.com

BRIEF-Concert Pharmaceuticals says announces CTP-543 positive top-line Phase 1 results

* Concert pharmaceuticals - CTP-543 well-tolerated across all dose groups in study & there were no serious adverse events in subjects who received CTP-543

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BRIEF-aTyr Pharma reports signals of clinical activity in genetically distinct Myopathies with Resolaris in exploratory trials

* Top-Line results from a completed phase 1b/2 trial for adult patients with limb-girdle muscular dystrophy 2b

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BRIEF-Catalyst Pharmaceuticals updates on trial for patients with congenital myasthenic syndromes

* "Continue to believe that we will report top-line results from this study in second half of 2017"

companyNews reuters.com

BRIEF-Ocera completes enrollment of Phase 2B study of OCR-002 in hepatic encephalopathy patients

* Ocera Therapeutics Inc - expect to report top-line data for OCR-002 in Q1 of 2017

governmentFilingsNews reuters.com

BRIEF-TherapeuticsMD reports positive top-line results from pivotal phase 3 replenish trial in postmenopausal women with moderate to severe vasomotor symptoms (vms) treated with tx-001hr

* TherapeuticsMD announces positive top-line results from pivotal phase 3 replenish trial in postmenopausal women with moderate to severe vasomotor symptoms (vms) treated with tx-001hr

governmentFilingsNews reuters.com

BRIEF-Lexicon reports top-line results from phase 2 clinical trial conducted in collaboration with JDRF

* Lexicon reports top-line results from phase 2 clinical trial conducted in collaboration with JDRF

governmentFilingsNews reuters.com

BRIEF-Neuroderm announces top-line results of pilot PK trial

* Neuroderm announces top-line results of pilot PK trial comparing ND0701 with commercial apomorphine

companyNews reuters.com

BRIEF-Aradigm announces top-line results from two phase 3 studies evaluating Pulmaquin

* Aradigm announces top-line results from two phase 3 studies evaluating pulmaquin for the chronic treatment of non-cystic fibrosis bronchiectasis patients with lung infections with pseudomonas aeruginosa

rbssHealthcareNews reuters.com

BRIEF-Pfizer announces positive top-line results from the pivotal comparative reflections B3271002 study for PF-05280014

* Pfizer announces positive top-line results from the pivotal comparative reflections B3271002 study for PF-05280014, a potential biosimilar to Herceptin1 (Trastuzumab) Source text for Eikon: Further company coverage:

rbssHealthcareNews reuters.com

BRIEF-Cerecor reports top-line data from CERC-301 Phase 2 study

* Cerecor reports top-line data from CERC-301 Phase 2 study for major depressive disorder

companyNews reuters.com

BRIEF-Momenta Pharmaceuticals says positive top-line phase 3 results for M923, a proposed Humira biosimilar

* Momenta Pharmaceuticals announces positive top-line phase 3 results for M923, a proposed Humira (adalimumab) biosimilar

companyNews reuters.com

BRIEF-Recro Pharma reports positive top-line results

* Recro pharma reports positive top-line results from pivotal Phase III clinical trial of IV meloxicam

rbssHealthcareNews reuters.com

BRIEF-Lilly to abandon Alzheimer's drug after late-stage failure

* Lilly announces top-line results of solanezumab phase 3 clinical trial

governmentFilingsNews reuters.com

BRIEF-Tenax Therapeutics completes enrollment in late-stage cardiac study

* Tenax therapeutics inc says 880 total patients enrolled; top-line data readout currently expected in january 2017

companyNews reuters.com

BRIEF-Catabasis Pharma provides edasalonexent and rare disease pipeline updates at investor day

* Catabasis Pharma- Top-line safety and efficacy results from placebo-controlled portion of movedmd phase 2 trial are expected in first half of Q1 2017

companyNews reuters.com

BRIEF-Gilead announces top-line results from two phase 3 studies

* Gilead Sciences Inc - non-inferiority was not achieved for key secondary endpoint of response rate in total symptom score (TSS)

rbssHealthcareNews reuters.com

BRIEF-Nabriva reports Q3 loss per share of $6.56

* Says expect to have top-line data available for both phase 3 clinical trials of Lefamulin in second half of 2017

rbssHealthcareNews reuters.com

BRIEF-Aclaris announces positive top-line phase 3 results for A-101 in treating seborrheic keratosis

* Aclaris Therapeutics Inc - pivotal data show topical treatment delivered statistically significant results, meeting all primary and secondary endpoints

rbssHealthcareNews reuters.com

BRIEF-Aeterna zentaris Q3 loss per share $0.61

* Aeterna Zentaris - believe have funds necessary to complete two pivotal clinical trials, to report top-line results on both, to file a nda for macrilen in first half of 2017

rbssHealthcareNews reuters.com

BRIEF-Galectin Therapeutics Q3 loss per share $0.19

* Galectin Therapeutics Inc- on track for reporting of top-line results in december of 2017 for nash-cx trial

rbssHealthcareNews reuters.com

BRIEF-Agile Therapeutics reports Q3 2016 financial results

* Agile Therapeutics Inc - top-line data expected in early January 2017; resubmission planned for first half 2017

governmentFilingsNews reuters.com

BRIEF-Innocoll announces top-line data from phase 3 trials

* Innocoll Holdings PLC - collaguard pre-clinical safety studies completed; ide submission on track for later this month

rbssHealthcareNews reuters.com

BRIEF-RedHill Biopharma provides update on ongoing phase III, phase II studies with Bekinda

* RedHill Biopharma Ltd - top-line results from both studies are expected in mid-2017

governmentFilingsNews reuters.com

BRIEF-Conatus Initiates phase 2b encore-ph clinical trial of emricasan in patients with Nash Cirrhosis

* Top-Line results from encore-ph clinical trial are expected in 2018.

marketsNews reuters.com

BRIEF-Trevena reports Q3 loss per share $0.57

* Oliceridine phase 3 pivotal efficacy trials progressing on schedule for top-line data in 1q17

rbssHealthcareNews reuters.com

BRIEF-Neurim Pharmaceuticals announces positive top-line results from phase III trial of Paediatric Prolonged-Release Melatonin

* Announces positive top-line results from pivotal phase III trial of Paediatric Prolonged-Release Melatonin (PEDPRM) for sleep disturbances in children with autism spectrum disorders (ASD) Source text for Eikon:

rbssHealthcareNews reuters.com

BRIEF-Capricor Therapeutics gives 12-month results from Dynamic

* Capricor therapeutics inc- expect to report top-line six-month data from hope in q1 of 2017

rbssHealthcareNews reuters.com

BRIEF-Opexa Therapeutics says failed in mid-stage study

* Opexa therapeutics inc - on oc 28, co announced top-line results from its phase 2b "abili-t" clinical trial

marketsNews reuters.com

BRIEF-Lexicon reports positive mid-stage data on diabetes drug

* Lexicon reports positive top-line results in phase 2 dose-ranging study for sotagliflozin in patients with type 1 diabetes

governmentFilingsNews reuters.com

BRIEF-Dipexium announces top-line data from onestep phase 3 trials

* Announces top-line data from onestep phase 3 trials with locilex in mild diabetic foot infection did not meet primary clinical endpoint of superiority versus vehicle plus standardized wound care

governmentFilingsNews reuters.com

BRIEF-Amgen announces positive top-line results from Xgeva (Denosumab) Phase 3 trial

* Amgen announces positive top-line results from Xgeva (Denosumab) Phase 3 trial for delay of bone complications in multiple Myeloma patients

companyNews reuters.com

BRIEF-Gilead Sciences says phase 2 study of GS-4997 in PAH did not achieve primary endpoint

* Gilead announces top-line phase 2 results for GS-4997 (Selonsertib) in Nonalcoholic Steatohepatitis (NASH), Pulmonary Arterial Hypertension (PAH) and Diabetic Kidney Disease (DKD)

rbssHealthcareNews reuters.com

BRIEF-Bavarian Nordic starts Phase 2 clinical trial of RSV vaccine

* Top-line results from study are anticipated around mid-2017

rbssHealthcareNews reuters.com

BRIEF-Medicines Co announces positive top-line results from day 90 interim analysis in ongoing Orion-1 Phase 2 study of PCSK9si

* Medicines company announces positive top-line results from day 90 interim analysis in ongoing orion-1 phase 2 study of pcsk9si

companyNews reuters.com

BRIEF-Peregrine Pharmaceuticals reports top-line data from phase III SUNRISE trial of Bavituximab

* Press release - Peregrine Pharmaceuticals reports top-line and initial biomarker data from phase III SUNRISE trial of Bavituximab in oral presentation at European Society for Medical Oncology (ESMO) 2016 congress

rbssHealthcareNews reuters.com

BRIEF-AnaptysBio reports ANB020 top-line early-stage clinical trial results

* Reports ANB020 top-line phase 1 clinical trial results; favorable safety and pharmacodynamic parameters demonstrated in healthy volunteers

governmentFilingsNews reuters.com

BRIEF-Intra-Cellular therapies announces top-line results from the second phase 3 trial of ITI-007

* Intra Cellular Therapies Inc - believe ITI-007 did not separate from placebo on pre-specified primary endpoint in study '302

rbssHealthcareNews reuters.com

BRIEF-Novan Inc expects top-line results in Q1 2017 for both SB204 phase 3 pivotal trials

* Novan Inc Co expects top-line results in Q1 of 2017 for both SB204 phase 3 pivotal trials Source text for Eikon: Further company coverage: ;))

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BRIEF-Corbus Pharmaceuticals to report top-line data from its phase 2 systemic sclerosis study

* Expects to report top-line data from its phase 2 clinical study in systemic sclerosis in Q4 of 2016 Source text for Eikon: Further company coverage:

marketsNews reuters.com

BRIEF-Galectin says announces top-line data from exploratory phase 2A pilot trial (NASH-FX)

* Galectin therapeutics announces top-line data from exploratory phase 2a pilot trial (nash-fx) with gr-md-02 in nash patients with advanced fibrosis

rbssHealthcareNews reuters.com

BRIEF-Lipocine announces positive top-line phase 2b study results for LPCN 1111

* Lipocine Inc says target Phase 3 dose met primary and secondary end points

rbssHealthcareNews reuters.com

BRIEF-Teva announces data from second phase 3 study of SD-809

* Teva announces positive top-line data from second phase 3 study of SD-809 in Tardive Dyskinesia (TD)

rbssHealthcareNews reuters.com

BRIEF-Mast reports top-line results from phase 3 study in Sickle Cell Disease

* No statistically significant differences between treatment groups in intent-to-treat population across 2 secondary efficacy endpoints

companyNews reuters.com

BRIEF-Pfizer reports positive top-line results from reflections B537-02 study for PF-06438179

* Results confirm similar efficacy of PF-06438179 (Infliximab-pfizer) to Remicade(REG) (Infliximab), in combination with Methotrexate

companyNews reuters.com

BRIEF-Amgen announces positive top-line results from phase 3 study

* Amgen announces positive top-line results from phase 3 study of prolia (denosumab) in patients receiving glucocorticoid therapy

rbssHealthcareNews reuters.com

BRIEF-CTI Biopharma announces top-line results from PERSIST-2 phase 3 trial of Pacritinib for high-risk patients with advanced Myelofibrosis

* CTI Biopharma announces top-line results from persist-2 phase 3 trial of pacritinib for high-risk patients with advanced myelofibrosis

rbssHealthcareNews reuters.com

BRIEF-Immunovaccine posts positive early stage trial results of DPX-survivac in ovarian cancer

* Immunovaccine announces additional positive top-line results from phase 1/1b clinical trial program with DPX-survivac in ovarian cancer

marketsNews reuters.com

BRIEF-Auris reports top-line results from TACTT2 trial with Keyzilen

* Reports top-line results from TACTT2 trial with Keyzilen in acute inner ear tinnitus

companyNews reuters.com

BRIEF-Auris reports top-line results from its TACTT2 trial

* Auris medical reports top-line results from TACTT2 trial with Keyzilen in acute inner ear tinnitus Source text for Eikon: Further company coverage:

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BRIEF-Indivior Plc announces positive top-line phase 3 study results for RBP-6000

* Announces positive top-line phase 3 pivotal study results for rbp-6000 buprenorphine monthly depot for treatment of opioid use disorder

rbssHealthcareNews reuters.com

BRIEF-Astrazeneca announces positive top-line data from two phase III SYMBICORT studies

* Astrazeneca announces positive top-line data from two phase III SYMBICORT studies

mergersNews reuters.com

BRIEF-Bristol-Myers' Opdivo fails late-stage study in patients with lung cancer

* Bristol-Myers Squibb announces top-line results from checkmate -026, a phase 3 study of Opdivo (nivolumab) in treatment-naïve patients with advanced non-small cell lung cancer

companyNews reuters.com

BRIEF-Eyegate Pharmaceuticals reports positive top-line data

* Eyegate announces positive top-line data from phase 1B/2A clinical trial of EGP-437 for treatment of post-operative inflammation and pain in cataract surgery patients Source text for Eikon: Further company coverage:

rbssHealthcareNews reuters.com

BRIEF-Heron Therapeutics reports positive top-line results from Phase 2 Studies of HTX-011

* HTX-011 statistically superior to standard-of-care bupivacaine solution on both pain intensity and opioid use

rbssHealthcareNews reuters.com

BRIEF-Recro Pharma reports positive results from Pivotal Phase III clinical trial

* Recro Pharma reports positive top-line results from Pivotal Phase III clinical trial of IV Meloxicam

rbssHealthcareNews reuters.com

BRIEF-Viking Therapeutics says positive top-line results from VK0214 study

* Viking Therapeutics announces positive top-line results from proof-of-concept study of VK0214 in in vivo model of X-linked Adrenoleukodystrophy (X-ALD)

rbssHealthcareNews reuters.com

BRIEF-Mast Therapeutics expects to report top-line data in September

* Provided guidance on anticipated timing for announcement of top-line data from epic study; expects to report top-line data in September 2016

companyNews reuters.com

BRIEF-Sage Therapeutics reports positive top-line results

* Sage reports positive top-line results including demonstration of 30-day durability from phase 2 clinical trial of Sage-547 in severe postpartum depression

companyNews reuters.com

BRIEF-Pfizer announces positive top-line results from phase 3 S-TRAC trial

* Pfizer announces positive top-line results from phase 3 S-TRAC trial of sutent (sunitinib) as adjuvant therapy in patients at high risk of recurrent renal cell carcinoma